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It first causes a local irritation, then after a few seconds a diminution of sensibility, the skin turning white and anaemic and covered with frost, which then is the proper time to operate.

This early subordinating of their physical impulses leads also to a disregard of the calls of nature, vs coupled with a silly squeamishness about attending to prompt evacuations and lays the train for lifelong discomforts and disturbances.

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